<html><head></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; "><span class="Apple-style-span" style="font-family: monospace; ">We are happy to announce the launch of our latest Ensembl release (e66):</span><span class="Apple-style-span" style="font-family: monospace; "> </span><span class="Apple-style-span" style="font-family: monospace; "><a href="http://www.ensembl.org/">http://www.ensembl.org/</a></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">Here are some highlights:</span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">Human: The human genome assembly is updated to GRCh37.p6, containing 124 assembly patches. The DNA sequence for the primary assembly (chromosomes 1-22, X, Y, unlocalized scaffolds and unplaced scaffolds) remains unchanged. The short sequence variants are now updated to dbSNP 135. A new regulatory consequence table shows regulatory features and motifs at the position of the SNP or other sequence variant.</span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">New species: Coelacanth (Latimeria chalumnae)</span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">New genome: The assembly for Ciona intestinalis is updated.</span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">A complete list of the changes in release 66 can be found at</span><span class="Apple-style-span" style="font-family: monospace; "> </span><span class="Apple-style-span" style="font-family: monospace; "><a href="http://www.ensembl.org/info/website/news.html">http://www.ensembl.org/info/website/news.html</a></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">For the latest news on the ensembl project visit our blog at</span><span class="Apple-style-span" style="font-family: monospace; "> </span><span class="Apple-style-span" style="font-family: monospace; "><a href="http://www.ensembl.info/">http://www.ensembl.info/</a></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">Best regards,</span><span class="Apple-style-span" style="font-family: monospace; "><br></span><span class="Apple-style-span" style="font-family: monospace; ">Harpreet</span></body></html>