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<div>Thank you, Will, that works.</div>
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<div>Was that mentioned somewhere in the documentation?</div>
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<div>-- </div>
<div>Gregory Dougherty</div>
<div><span class="Apple-style-span" style="font-family: Arial; font-size: 13px; ">Sr. Analyst/Programmer | Information Technology</span><span class="Apple-style-span" style="font-family: Arial; font-size: 13px; "><br>
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</span><span class="Apple-style-span" style="font-family: Arial; font-size: 13px; ">(507) 284-8493 | dougherty.gregory@mayo.edu</span><span class="Apple-style-span" style="font-family: Arial; font-size: 13px; "><font color="#0000FF"><br>
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<span style="font-weight:bold">From: </span>Will McLaren <<a href="mailto:wm2@ebi.ac.uk">wm2@ebi.ac.uk</a>><br>
<span style="font-weight:bold">Reply-To: </span>Ensembl developers list <<a href="mailto:dev@ensembl.org">dev@ensembl.org</a>><br>
<span style="font-weight:bold">Date: </span>Friday, December 21, 2012 11:27 AM<br>
<span style="font-weight:bold">To: </span>Ensembl developers list <<a href="mailto:dev@ensembl.org">dev@ensembl.org</a>><br>
<span style="font-weight:bold">Subject: </span>Re: [ensembl-dev] VEP version 2.7 performance is pitiful when providing parameters from a config file<br>
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<div dir="ltr">Hi Gregory,
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<div style="">You need a "1" after the cache and offline options in the config file, otherwise that option will be ignored.</div>
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<div style="">cache  1</div>
<div style="">offline  1</div>
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<div style="">In fact, you don't need to specify both cache and offline, since cache is implied by offline - just offline will do.</div>
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<div style="">Regards and Merry Christmas!</div>
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<div style="">Will McLaren</div>
<div style="">Ensembl Variation</div>
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<div class="gmail_quote">On 21 December 2012 16:43, Dougherty, Gregory T. <span dir="ltr">
<<a href="mailto:Dougherty.Gregory@mayo.edu" target="_blank">Dougherty.Gregory@mayo.edu</a>></span> wrote:<br>
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<div>If I use the attached config file with an installation that has the specified cache file, I get a performance of 1 variant / second on a specific vcf file.  If I run the exact same options from the command line, I get 150+ variants / second.</div>
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<div>Why does the config file give such horrible performance?</div>
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<div>-- </div>
<div>Gregory Dougherty</div>
<div><span style="font-family:Arial;font-size:13px">Sr. Analyst/Programmer | Information Technology</span><span style="font-family:Arial;font-size:13px"><br>
</span><span style="font-family:Arial;font-size:13px">41st Street Professional Building</span><span style="font-family:Arial;font-size:13px"><br>
</span><span style="font-family:Arial;font-size:13px">Ff 3-410-C</span><span style="font-family:Arial;font-size:13px"><br>
</span><span style="font-family:Arial;font-size:13px"><a href="tel:%28507%29%20284-8493" value="+15072848493" target="_blank">(507) 284-8493</a> |
<a href="mailto:dougherty.gregory@mayo.edu" target="_blank">dougherty.gregory@mayo.edu</a></span><span style="font-family:Arial;font-size:13px"><font color="#0000FF"><br>
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