<div dir="ltr">One small addition: while Ensembl and RefSeq models can differ with regard to their outer bounds, they can also slightly differ with regard to their sequence. Ensembl models are based on the reference assembly, while RefSeq models are based on the cDNA sequence.<div>
<br></div><div>Cheers,</div><div>Bert</div></div><div class="gmail_extra"><br><br><div class="gmail_quote">On Tue, Feb 25, 2014 at 10:34 AM, Andy Yates <span dir="ltr"><<a href="mailto:ayates@ebi.ac.uk" target="_blank">ayates@ebi.ac.uk</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">Hi Duarte,<br>
<br>
So there a point that both gene sets do come from different institutes and funding streams and we want to maintain the best service to our users. Historically we have provided both gene sets separately as we felt this was the best way, at the time, to serve our users. However we are discussing how to have better links between Ensembl and RefSeq. One of the options is generating an über gene set similar to the one you have mentioned. This is still in the very early stages of discussion and is a non-trivial process. We will keep you & everyone else informed of any developments.<br>

<br>
All the best,<br>
<br>
Andy<br>
<br>
------------<br>
Andrew Yates - Ensembl Support Coordinator<br>
European Bioinformatics Institute (EMBL-EBI)<br>
European Molecular Biology Laboratory<br>
Wellcome Trust Genome Campus<br>
Hinxton<br>
Cambridge CB10 1SD<br>
Tel: <a href="tel:%2B44-%280%291223-492538" value="+441223492538">+44-(0)1223-492538</a><br>
Fax: <a href="tel:%2B44-%280%291223-494468" value="+441223494468">+44-(0)1223-494468</a><br>
<a href="http://www.ensembl.org/" target="_blank">http://www.ensembl.org/</a><br>
<div class="HOEnZb"><div class="h5"><br>
On 24 Feb 2014, at 21:18, Duarte Molha <<a href="mailto:duartemolha@gmail.com">duartemolha@gmail.com</a>> wrote:<br>
<br>
> Sorry if it is a stupid question... but why not? is there some reason why the two datasets could not be merged?<br>
><br>
> I would love to be able to do all my analysis using Ensembl but many of my clients rely on refseq entities. It would be great if they could be merged and be each NM transcript be identifiable directly in ensembl.<br>

><br>
><br>
> On Mon, Feb 24, 2014 at 12:34 PM, Andy Yates <<a href="mailto:ayates@ebi.ac.uk">ayates@ebi.ac.uk</a>> wrote:<br>
> what you expect from us (WRT lowest & highest) is what we are doing. As for Ensembl and RefSeq transcripts the two sets of models are s<br>
><br>
><br>
><br>
> =========================<br>
>      Duarte Miguel Paulo Molha<br>
>          <a href="http://about.me/duarte" target="_blank">http://about.me/duarte</a><br>
> =========================<br>
</div></div><div class="HOEnZb"><div class="h5">> _______________________________________________<br>
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> Ensembl Blog: <a href="http://www.ensembl.info/" target="_blank">http://www.ensembl.info/</a><br>
<br>
<br>
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</div></div></blockquote></div><br><br clear="all"><div><br></div>-- <br><div dir="ltr">Bert Overduin, Ph.D.<br>Vertebrate Genomics Team<br><br>European Bioinformatics Institute (EMBL-EBI)<br>European Molecular Biology Laboratory<br>
Wellcome Trust Genome Campus<br>Hinxton<br>Cambridge CB10 1SD<br>United Kingdom<br><br><a href="http://www.ebi.ac.uk/~bert" target="_blank">http://www.ebi.ac.uk/~bert</a><div><p style="margin-bottom:0in;margin-bottom:.0001pt">
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