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      Dear Magali,<br>
      <br>
      Thank you for your replay and your support. Could you describe
      briefly vep cache? is something like memcached?<br>
      <br>
      At the moment, I don't think that I need faster performance on
      other species, but I will remember your suggestion.<br>
      <br>
      Regards,<br>
      <br>
      Paolo.<br>
      <br>
      <br>
      <br>
      Il 22/07/2014 18:36, mag ha scritto:<br>
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      Hi Paolo,<br>
      <br>
      Thank you for reporting this and apologies for the error.<br>
      <br>
      We were wrongly using some human-specific configuration for all
      species, this has now been fixed on the live server.<br>
      <br>
      If you are using POST requests for VEP, please be aware that only
      human uses the vep cache.<br>
      For other species, we are still using direct database connection,
      which will result in lower performance.<br>
      <br>
      If you are interested in getting faster POST support for other
      species, please contact us.<br>
      <br>
      <br>
      Regards,<br>
      Magali<br>
      <br>
      <div class="moz-cite-prefix">On 22/07/2014 11:55, Paolo Cozzi
        wrote:<br>
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        Dear developer,<br>
        <br>
        I found an odd response from the
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        <a moz-do-not-send="true"
          href="http://rest.ensembl.org/documentation/info/vep_region_post"
          style="color: rgb(0, 85, 128); text-decoration: underline;
          outline: 0px; font-family: 'Helvetica Neue', Helvetica, Arial,
          sans-serif; font-size: 14px; font-style: normal; font-variant:
          normal; font-weight: normal; letter-spacing: normal;
          line-height: 20px; orphans: auto; text-align: left;
          text-indent: 0px; text-transform: none; white-space: normal;
          widows: auto; word-spacing: 0px; -webkit-text-stroke-width:
          0px;">vep/:species/region/</a> of the new ensembl REST server
        (
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        <a moz-do-not-send="true" href="http://rest.ensembl.org/">http://rest.ensembl.org/</a>)
        while searching for species other than human. For example, if I
        do 2 POST request with curl on human and cow (the sample data
        are the same as in the VEP webserver):<br>
        <br>
        $ curl -H "content-type:application/json" -H
        "accept:application/json" --data '{ "variants" : ["1  909238 
        909238  G/C  +", "3  361464  361464  A/-  +", "5  121187650 
        121188519  DUP"] }' <a moz-do-not-send="true"
          class="moz-txt-link-freetext"
          href="http://rest.ensembl.org/vep/human/region">http://rest.ensembl.org/vep/human/region</a>
        > output_human.txt<br>
        <br>
        $ curl -H "content-type:application/json" -H
        "accept:application/json" --data '{ "variants" : ["1  909238 
        909238  G/C  +", "3  361464  361464  A/-  +", "5  121187650 
        121188519  DUP"] }' <a moz-do-not-send="true"
          class="moz-txt-link-freetext"
          href="http://rest.ensembl.org/vep/cow/region">http://rest.ensembl.org/vep/cow/region</a>
        > output_cow.txt <br>
        <br>
        I will find the same results (diff give me no output), even VEP
        gives me 2 different results. Could be a problem of variation
        endpoint?<br>
        <br>
        Thanks for your support,<br>
        <br>
        best regards,<br>
        <br>
        Paolo.<br>
        <br>
        <br>
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