<div dir="ltr">Hello,<div><br></div><div>The VEP endpoint is used to predict the effects of _any_ arbitrary position and allele that you input. The coordinates that you input do not have to correspond to a known variant (e.g. from dbSNP).</div><div><br></div><div>If you do input coordinates of a known variant, then the ID and related information for this variant will be reported too (e.g. <a href="http://grch37.rest.ensembl.org/vep/human/region/1:230845794-230845794/C">http://grch37.rest.ensembl.org/vep/human/region/1:230845794-230845794/C</a>).</div><div><br></div><div>The Overlap endpoint is used to find known variants that overlap a region.</div><div><br></div><div>Regards</div><div><br></div><div>Will McLaren</div><div>Ensembl Variation</div></div><div class="gmail_extra"><br><div class="gmail_quote">On 29 June 2015 at 20:12, Igo Medeiros <span dir="ltr"><<a href="mailto:igo701@gmail.com" target="_blank">igo701@gmail.com</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr">I was finding into database, but i didn't find too.<br></div><div class="HOEnZb"><div class="h5"><div class="gmail_extra"><br><div class="gmail_quote">2015-06-29 13:59 GMT-03:00 Igo Medeiros <span dir="ltr"><<a href="mailto:igo701@gmail.com" target="_blank">igo701@gmail.com</a>></span>:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div><div><div><div>Thank you for help.<br></div>I have other question about rest.<br></div>I am using this link <a href="http://grch37.rest.ensembl.org/vep/human/region/22:30163533-30163533/C" target="_blank">http://grch37.rest.ensembl.org/vep/human/region/22:30163533-30163533/C</a>? to find a mutation, but i noticed that when i use <a href="http://grch37.rest.ensembl.org/overlap/region/human/22:30162533-30165533?feature=variation" target="_blank">http://grch37.rest.ensembl.org/overlap/region/human/22:30162533-30165533?feature=variation</a>; i don't find, in this interval, the mutation that i found in rest.vep.<br></div>Is there some way that i can pass the interval in rest.vep whitout the allele?<br><br></div>Thank you for attention.<br></div><div><div><div class="gmail_extra"><br><div class="gmail_quote">2015-06-29 8:52 GMT-03:00 Will McLaren <span dir="ltr"><<a href="mailto:wm2@ebi.ac.uk" target="_blank">wm2@ebi.ac.uk</a>></span>:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr">Hello,<div><br></div><div>The variation ID endpoint gives clinical significance and phenotype (disease) information, e.g. </div><div><br></div><div><a href="http://rest.ensembl.org/variation/human/rs699?content-type=application/json&phenotypes=1" target="_blank">http://rest.ensembl.org/variation/human/rs699?content-type=application/json&phenotypes=1</a><br></div><div><br></div><div>Documentation is here: <a href="http://rest.ensembl.org/documentation/info/variation_id" target="_blank">http://rest.ensembl.org/documentation/info/variation_id</a></div><div><br></div><div>Study information is not currently available via our REST API.</div><div><br></div><div>Regards</div><div><br></div><div>Will McLaren</div><div>Ensembl Variation</div></div><div class="gmail_extra"><br><div class="gmail_quote"><div><div>On 29 June 2015 at 12:15, Igo Medeiros <span dir="ltr"><<a href="mailto:igo701@gmail.com" target="_blank">igo701@gmail.com</a>></span> wrote:<br></div></div><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div><div><div dir="ltr"><div><div>Hi ENsembl Team,<br></div>I am using rest, but I need the information about clinical significance, disease and study, but I am not find there. How can I find this informations in rest?<br></div>I was looking at documentation, but not found.<span><font color="#888888"><br clear="all"><div><div><div><br></div><div>-- <br><div>Igo Paixão de Medeiros</div>
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