<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=us-ascii"><meta name=Generator content="Microsoft Word 14 (filtered medium)"><style><!--
/* Font Definitions */
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:Consolas;
panose-1:2 11 6 9 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
margin-bottom:.0001pt;
font-size:11.0pt;
font-family:"Calibri","sans-serif";
mso-fareast-language:EN-US;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:purple;
text-decoration:underline;}
span.Code
{mso-style-name:Code;
mso-style-priority:1;
font-family:Consolas;
border:none;
background:#F2F2F2;}
p.CodeBlock, li.CodeBlock, div.CodeBlock
{mso-style-name:"Code Block";
margin-top:6.0pt;
margin-right:14.2pt;
margin-bottom:6.0pt;
margin-left:14.2pt;
mso-add-space:auto;
background:#F2F2F2;
font-size:11.0pt;
font-family:Consolas;}
p.CodeBlockCxSpFirst, li.CodeBlockCxSpFirst, div.CodeBlockCxSpFirst
{mso-style-name:"Code BlockCxSpFirst";
mso-style-type:export-only;
margin-top:6.0pt;
margin-right:14.2pt;
margin-bottom:0cm;
margin-left:14.2pt;
margin-bottom:.0001pt;
mso-add-space:auto;
background:#F2F2F2;
font-size:11.0pt;
font-family:Consolas;}
p.CodeBlockCxSpMiddle, li.CodeBlockCxSpMiddle, div.CodeBlockCxSpMiddle
{mso-style-name:"Code BlockCxSpMiddle";
mso-style-type:export-only;
margin-top:0cm;
margin-right:14.2pt;
margin-bottom:0cm;
margin-left:14.2pt;
margin-bottom:.0001pt;
mso-add-space:auto;
background:#F2F2F2;
font-size:11.0pt;
font-family:Consolas;}
p.CodeBlockCxSpLast, li.CodeBlockCxSpLast, div.CodeBlockCxSpLast
{mso-style-name:"Code BlockCxSpLast";
mso-style-type:export-only;
margin-top:0cm;
margin-right:14.2pt;
margin-bottom:6.0pt;
margin-left:14.2pt;
mso-add-space:auto;
background:#F2F2F2;
font-size:11.0pt;
font-family:Consolas;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri","sans-serif";
color:windowtext;}
p.QuoteBlock, li.QuoteBlock, div.QuoteBlock
{mso-style-name:"Quote Block";
margin-top:6.0pt;
margin-right:0cm;
margin-bottom:6.0pt;
margin-left:36.0pt;
line-height:150%;
border:none;
padding:0cm;
font-size:11.0pt;
font-family:"Calibri","sans-serif";
mso-fareast-language:EN-US;}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri","sans-serif";
mso-fareast-language:EN-US;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:72.0pt 72.0pt 72.0pt 72.0pt;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]--></head><body lang=EN-GB link=blue vlink=purple><div class=WordSection1><p class=MsoNormal>Hi,<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>Are misconversions by the Assembly Converter being fixed?<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>On the GRCh38 EnsEMBL browser page for CHD2 (<a href="http://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000173575">http://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000173575</a>), it states “This gene maps to 93,443,419-93,571,235 in GRCh37 coordinates.” However, the GRCh37 page (<a href="http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000173575">http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000173575</a>) shows the co-ordinates as “Chromosome 15: 93,426,526-93,571,237”.<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>These co-ordinates are the same as the “Assembly Converter” conversion, from which I assume the browser takes its data.<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><span style='mso-fareast-language:EN-GB'>Kind regards,<o:p></o:p></span></p><p class=MsoNormal><span style='mso-fareast-language:EN-GB'>Luke<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p></div><br /><br /><p style="font-family: Verdana; font-size:10pt; color:#666666;"><b>Disclaimer</b></p><p style="font-family: Verdana; font-size:8pt; color:#666666;">The information contained in this communication from the sender is confidential. It is intended solely for use by the recipient and others authorized to receive it. If you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful.<br /><br />This email has been scanned for viruses and malware, and may have been automatically archived by <b>Mimecast Ltd</b>, an innovator in Software as a Service (SaaS) for business. Providing a <b>safer</b> and <b>more useful</b> place for your human generated data. Specializing in; Security, archiving and compliance. To find out more <a href="http://www.mimecast.com/products/" target="_blank">Click Here</a>.</p></body></html>