<html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"></head><body dir="auto"><div>As a clarification, the GRCh37 site is based on Ensembl release 75 with selected data updates and regular updates to the API and website. </div><div><br></div><div>From the GRCh37 site:</div><div><br></div><div><p style="margin: 0px 0px 2em; line-height: 1.25em; padding: 0px;"><span style="background-color: rgba(255, 255, 255, 0);">"This archive is based on Ensembl Release 75 data, and gives continuing access to human assembly GRCh37, as well as all our other release 75 species (data freeze March 2014) for comparative purposes. Human variation and regulation data has since been updated in March 2015.</span></p><p style="margin: 0px 0px 1em; line-height: 1.25em; padding: 0px;"><span style="background-color: rgba(255, 255, 255, 0);">The API and website will be updated in tandem with the release of the main Ensembl website, and we will also periodically update this site with new human data, which will be announced in this panel."</span></p></div><div><br></div><div>I hope this helps. </div><div><br></div><div>Paul</div><div><br></div><div><br></div><div>On 11 Oct 2016, at 15:31, Matthew Laird <<a href="mailto:lairdm@ebi.ac.uk">lairdm@ebi.ac.uk</a>> wrote:<br><br></div><blockquote type="cite"><div><span>Hi Wolf,</span><br><span></span><br><span>If I'm understanding what you're describing, I'm assuming you're looking at GRCh37 Biomart for this inconsistency. While we maintain GRCh37 archives, we no longer actively update xrefs for that assembly, they're all frozen as of Ensembl release 37. Looking up HYDIN in Ensembl 86, GRCh38 I see only 610812 is returned for this HGNC symbol, so whatever mis-mapping was occurring seems to be corrected.</span><br><span></span><br><span>If I'm misunderstanding the issue you're raising, please let us know. Thanks.</span><br><span></span><br><span>On 11/10/16 12:11, Wolf Beat wrote:</span><br><blockquote type="cite"><span>Hi,</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>i had an interesting issue with the OMIM number for a certain gene, HYDIN.</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>When querying biomart, i get two OMIM numbers back for this gene:</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>HYDROCEPHALUS-INDUCING, MOUSE, HOMOLOG OF, 2; HYDIN2 610813</span><br></blockquote><blockquote type="cite"><span>and</span><br></blockquote><blockquote type="cite"><span>HYDROCEPHALUS-INDUCING, MOUSE, HOMOLOG OF; HYDIN 610812</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>The Problem, the first one is wrong. The first one is for the HYDIN2 gene, which is located on chromosome 1. HYDIN is on chromosome 16.</span><br></blockquote><blockquote type="cite"><span>Looking at the OMIM pages linked this is confirmed:</span><br></blockquote><blockquote type="cite"><span>HYDIN: <a href="http://omim.org/entry/610812">http://omim.org/entry/610812</a></span><br></blockquote><blockquote type="cite"><span>HYDIN2: <a href="http://omim.org/entry/610813">http://omim.org/entry/610813</a></span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>And here the ensembl pages:</span><br></blockquote><blockquote type="cite"><span>HYDIN: <a href="http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000157423;r=16:70807378-71230722">http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000157423;r=16:70807378-71230722</a></span><br></blockquote><blockquote type="cite"><span>HYDIN2: <a href="http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000239475;r=1:146310555-146349531">http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000239475;r=1:146310555-146349531</a></span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>So my question is, is this an error on the part of ensembl (wrong annotation), some misunderstanding of my part and can i fix/detect this problem on my side?</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>Thank you very much.</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>Kind regards</span><br></blockquote><blockquote type="cite"><span></span><br></blockquote><blockquote type="cite"><span>Beat Wolf</span><br></blockquote><blockquote type="cite"><span>_______________________________________________</span><br></blockquote><blockquote type="cite"><span>Dev mailing list <a href="mailto:Dev@ensembl.org">Dev@ensembl.org</a></span><br></blockquote><blockquote type="cite"><span>Posting guidelines and subscribe/unsubscribe info: <a href="http://lists.ensembl.org/mailman/listinfo/dev">http://lists.ensembl.org/mailman/listinfo/dev</a></span><br></blockquote><blockquote type="cite"><span>Ensembl Blog: <a href="http://www.ensembl.info/">http://www.ensembl.info/</a></span><br></blockquote><span></span><br><span></span><br><span>_______________________________________________</span><br><span>Dev mailing list <a href="mailto:Dev@ensembl.org">Dev@ensembl.org</a></span><br><span>Posting guidelines and subscribe/unsubscribe info: <a href="http://lists.ensembl.org/mailman/listinfo/dev">http://lists.ensembl.org/mailman/listinfo/dev</a></span><br><span>Ensembl Blog: <a href="http://www.ensembl.info/">http://www.ensembl.info/</a></span><br></div></blockquote></body></html>