<html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"></head><body dir="auto"><div><p style="margin: 0px; font-size: 12px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-width: initial; -webkit-text-stroke-color: rgb(0, 0, 0);"><span style="font-size: 12pt;">Cheers, my name is Alejandro and I have doubts about DRD2 gene annoted in the two last versions of the reference human genome (GRCh37 and GRCh38), the questions are the next:</span></p>
<p style="margin: 0px; font-size: 12px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-width: initial; -webkit-text-stroke-color: rgb(0, 0, 0);"><span style="font-size: 12pt;">I noticed that an isoform for gene DRD2 is absent in the new version of genome (GRCh38), I would like to know what does it mean and in addition I would like to know if this is related with the other isoforms which have been moved from their habitual coordinates and sizes in the last version</span></p>
<p style="margin: 0px; font-size: 12px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-width: initial; -webkit-text-stroke-color: rgb(0, 0, 0); min-height: 13.8px;"><span style="font-size: 12pt;"></span><br></p>
<p style="margin: 0px; font-size: 12px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-width: initial; -webkit-text-stroke-color: rgb(0, 0, 0);"><span style="font-size: 12pt;">I will be waiting for your answer </span></p>
<p style="margin: 0px; font-size: 12px; line-height: normal; font-family: Helvetica; -webkit-text-stroke-width: initial; -webkit-text-stroke-color: rgb(0, 0, 0);"><span style="font-size: 12pt;">All the best</span></p>Alejandro G. </div></body></html>