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Dear Daniel,<br>
<br>
Thank you for reporting this, it is definitely not expected
behaviour.<br>
We will investigate the problem and let you know when a fix is
available.<br>
<br>
<br>
Kind regards,<br>
Magali<br>
<br>
<div class="moz-cite-prefix">On 16/06/2017 13:50, Daniel Suveges
wrote:<br>
</div>
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<p class="MsoNormal"><span style="font-size:11.0pt">Ok, I have
to adjust my question: apparently sometimes the query
returns the expected coordinates, but mostly the return is
empty. I hope this helps.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">(On the
attached screenshot you can see that the response to the
same query sometimes empty, sometimes not.)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Best,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Daniel<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<div style="border:none;border-top:solid #B5C4DF
1.0pt;padding:3.0pt 0cm 0cm 0cm">
<p class="MsoNormal"><b><span style="color:black">From: </span></b><span
style="color:black">Dev <a class="moz-txt-link-rfc2396E" href="mailto:dev-bounces@ensembl.org"><dev-bounces@ensembl.org></a> on
behalf of Daniel Suveges <a class="moz-txt-link-rfc2396E" href="mailto:ds26@sanger.ac.uk"><ds26@sanger.ac.uk></a><br>
<b>Reply-To: </b>Ensembl developers list
<a class="moz-txt-link-rfc2396E" href="mailto:dev@ensembl.org"><dev@ensembl.org></a><br>
<b>Date: </b>Friday, 16 June 2017 at 13:16<br>
<b>To: </b>Ensembl developers list
<a class="moz-txt-link-rfc2396E" href="mailto:dev@ensembl.org"><dev@ensembl.org></a><br>
<b>Subject: </b>[ensembl-dev] REST - map endpoint</span><span
style="color:black;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
</div>
<div>
<p class="MsoNormal"><span style="font-family:"Times New
Roman""><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">Hi
Guys,</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">I’m
trying to use the map endpoint of the REST service (to map
between the human GRCh37 and 38 build) and I’m encountering
some unexpected behavior:</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">Let’s
take the variant rs11553699 for example:
</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">it’s
GRCh37 coordinates:
</span><span style="font-size:11.0pt">12:122216910</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">it’s
GRCh38 coordinates:
</span><span style="font-size:11.0pt">12:121779004</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">If
I want to map it’s GRCh37 coordinates to the newer build it
works:</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"><a
href="http://rest.ensembl.org/map/human/GRCh37/12:122216910..122216910:1/GRCh38?content-type=application/json"
moz-do-not-send="true">http://rest.ensembl.org/map/human/GRCh37/12:122216910..122216910:1/GRCh38?content-type=application/json</a></span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">But
when I’m trying to do the same in the opposite direction,
the ‘mappings’ array is empty in the returned json:</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"><a
href="http://rest.ensembl.org/map/human/GRCh38/12:121779004..121779004:1/GRCh37?content-type=application/json"
moz-do-not-send="true">http://rest.ensembl.org/map/human/GRCh38/12:121779004..121779004:1/GRCh37?content-type=application/json</a></span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">For
other GRCh38 coordinates mapping works, this position has
coordinates in both build, so it is not clear to me why the
second query seemingly fails.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">Thank
you very much for your help!</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">Best,</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt" lang="EN-US">Daniel</span><o:p></o:p></p>
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