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<p>Hi Bhavana,</p>
Thanks for reporting this one. It will be fixed when we update our
REST servers for our new release next month. If you are running VEP
on the command line, you can pick up the fix by updating your copy
of the ensembl-variation API.<br>
<br>
Sorry for the delay in getting back to you - do let us know if you
spot any other odd cases.<br>
<br>
Best wishes,<br>
<br>
Sarah<br>
<br>
<div class="moz-cite-prefix">On 10/07/2017 16:23, Bhavana Harsha
wrote:<br>
</div>
<blockquote
cite="mid:9CD683DA-9A3F-4EFF-BCAC-3CFD519CB3A8@sanger.ac.uk"
type="cite">
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Hello,
<div class=""><br class="">
</div>
<div class="">I’m trying to look at the transcript consequences of
the following variant:</div>
<div class="">17:g.7577607_7578174del</div>
<div class=""><br class="">
</div>
<div class="">using the REST API like this:</div>
<div class=""><a moz-do-not-send="true"
href="http://grch37.rest.ensembl.org/vep/human/hgvs/17:g.7577607_7578174del?content-type=application/json;xref_refseq=1&canonical=1&ccds=1&hgvs=1"
class="">http://grch37.rest.ensembl.org/vep/human/hgvs/17:g.7577607_7578174del?content-type=application/json;xref_refseq=1&canonical=1&ccds=1&hgvs=1</a></div>
<div class=""><br class="">
</div>
<div class="">This is what I get for one of the transcripts:</div>
<div class="">ENST00000269305.4:c.674_672+3delCTGG….</div>
<div class=""><br class="">
</div>
<div class="">Shouldn’t the correct syntax be ENST00000269305.4:c.<b
class="">672+3_674</b>delCTGG..?</div>
<div class=""><br class="">
</div>
<div class="">(Other transcript consequences for this variant
appear to have a similar issue
- ENST00000504290.1:n.556_554+3delCTGGT…)</div>
<div class=""><br class="">
</div>
<div class="">I get the same result using the VEP web interface.</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class="">Regards,</div>
<div class="">Bhavana</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class=""><br class="">
</div>
<div class="">
<div style="color: rgb(0, 0, 0); font-family: Helvetica;
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<br class="Apple-interchange-newline">
---------------------------------------------<br class="">
Bhavana Harsha<br class="">
Bioinformatician<br class="">
COSMIC<br class="">
Wellcome Trust Sanger Institute<br class="">
Hinxton, UK<br class="">
CB10 1SA<br class="">
</div>
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font-size: 12px; font-style: normal; font-variant: normal;
font-weight: normal; letter-spacing: normal; orphans: auto;
text-align: start; text-indent: 0px; text-transform: none;
white-space: normal; widows: auto; word-spacing: 0px;
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