<html><head><meta http-equiv="Content-Type" content="text/html charset=us-ascii"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class="">Hi Pankaj,<div class=""><br class=""></div><div class="">Yes, the mouse reference genome assembly presented in Ensembl is based on the C57BL/6J strain:</div><div class=""><a href="http://www.ensembl.org/Mus_musculus/Info/Annotation" class="">http://www.ensembl.org/Mus_musculus/Info/Annotation</a></div><div class=""><br class=""></div><div class="">The genome assembly is called GRCm38 as was produced by the Genome Reference Consortium (GRC):</div><div class=""><a href="https://www.ncbi.nlm.nih.gov/grc/mouse" class="">https://www.ncbi.nlm.nih.gov/grc/mouse</a></div><div class=""><br class=""></div><div class="">Best wishes</div><div class=""><br class=""></div><div class="">Ben</div><div class="">Ensembl Helpdesk</div><div class=""><br class=""></div><div class=""><br class=""></div><div class=""><div><blockquote type="cite" class=""><div class="">On 28 Sep 2017, at 12:38, Pankaj Agarwal <<a href="mailto:p.agarwal@duke.edu" class="">p.agarwal@duke.edu</a>> wrote:</div><br class="Apple-interchange-newline"><div class=""><div class="WordSection1" style="page: WordSection1; font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;"><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class="">Hi,<o:p class=""></o:p></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class="">I was writing to ask if the mouse reference genome is based on the Black 6 (C57BL/6J) strain or some other or it is a combination.<o:p class=""></o:p></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class="">There is a cell line genomic data set from C57BL/6J strain that I need to align to the reference and I wanted to check if the latest available reference in Ensembl would be the best.<o:p class=""></o:p></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class="">Thanks,<o:p class=""></o:p></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class="">- Pankaj<o:p class=""></o:p></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><o:p class=""> </o:p></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">-----------------------------<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Pankaj Agarwal, M.S<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Bioinformatician<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Data Analyst<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Applied Therapeutics<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Div. of Surgical Sciences<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Dept. of Surgery<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">Duke University<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">M: 919-244-6389<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class="">O: 919-681-2251<o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><span style="font-size: 7pt; font-family: Verdana, sans-serif;" class=""><a href="mailto:p.agarwal@duke.edu" style="color: purple; text-decoration: underline;" class=""><span style="color: blue;" class="">p.agarwal@duke.edu</span></a><o:p class=""></o:p></span></div><div style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Calibri, sans-serif;" class=""><o:p class=""> </o:p></div></div><span style="font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; 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text-decoration: underline; font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;" class="">Dev@ensembl.org</a><br style="font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;" class=""><span style="font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; float: none; display: inline !important;" class="">Posting guidelines and subscribe/unsubscribe info:<span class="Apple-converted-space"> </span></span><a href="http://lists.ensembl.org/mailman/listinfo/dev" style="color: purple; text-decoration: underline; font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;" class="">http://lists.ensembl.org/mailman/listinfo/dev</a><br style="font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;" class=""><span style="font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; float: none; display: inline !important;" class="">Ensembl Blog:<span class="Apple-converted-space"> </span></span><a href="http://www.ensembl.info/" style="color: purple; text-decoration: underline; font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;" class="">http://www.ensembl.info/</a></div></blockquote></div><br class=""><div apple-content-edited="true" class="">
<div style="color: rgb(0, 0, 0); letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class=""><div style="color: rgb(0, 0, 0); letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class=""><div class="">Ben Moore</div><div class="">Ensembl Outreach Officer</div><div class=""><br class=""></div><div class="">European Bioinformatics Institute (EMBL-EBI)</div><div class="">European Molecular Biology Laboratory</div><div class="">Wellcome Trust Genome Campus</div><div class="">Hinxton</div><div class="">Cambridge</div><div class="">CB10 1SD</div><div class="">UK</div><div class=""><br class=""></div><div class=""><a href="mailto:bmoore@ebi.ac.uk" class="">bmoore@ebi.ac.uk</a></div><div class="">+44 (0)1223 494265</div></div></div>
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