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<p>Hi Mike,</p>
<p>COSMIC licensing has changed and the new terms longer permit us
to redistribute the alleles observed. We can still provide
locations and ids to allow you to look up information on the
COSMIC site. There is full information here:<br>
</p>
<p><a class="moz-txt-link-freetext" href="http://cancer.sanger.ac.uk/cosmic/license">http://cancer.sanger.ac.uk/cosmic/license</a></p>
<p>Best wishes,</p>
<p>Sarah<br>
</p>
<br>
<div class="moz-cite-prefix">On 21/03/2018 16:34, D'Eletto, Michael
wrote:<br>
</div>
<blockquote type="cite"
cite="mid:a6d24c28-f70f-003a-16c2-3782ba4b117a@ynhh.org">
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<p>Hi Ensembl dev team,</p>
<p>I had a question regarding the VEP caches and changes made to
co-located COSMIC variants. We've been using an older cache
version of regulatory reasons in our lab, so I just noticed this
update on new versions. It seems that older versions of the
cache (up until release 85) described the variant allele change
in the cache, but starting in release 85, this variant allele
change now says "COSMIC_MUTATION" instead. Is there a reason
for this change? We found it useful for the VEP to report out
only the COSMIC variant that matched that specific allele change
(e.g. when using with --checking_existing) and not all COSMIC
variants at a position.</p>
<pre style="color: rgb(0, 0, 0); font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-style: initial; text-decoration-color: initial;"> {
"phenotype_or_disease": 1,
"end": 21971208,
"seq_region_name": 9,
"somatic": 1,
"allele_string": "COSMIC_MUTATION",
"start": 21971208,
"id": "COSM12537",
"strand": 1
}</pre>
<p>Thanks,</p>
<p>Mike D'Eletto<br>
</p>
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