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<p>Hi Fin,</p>
<p>Thanks for the suggestion; we'll look into it.<br>
</p>
We take the evidence statuses and frequency data for different
sources, which can lead to discrepancies in a small minority of
cases. When we import data from dbSNP, we extract the names of the
data submitters and use this to create the evidence status. The
frequency and any genotype data is taken from VCF, often direct from
the project. If there is more frequency data available direct from
gnomAD say than has been submitted to, or clustered into a RefSeq
record by dbSNP, you will see frequency data but no evidence. (We
don't like to withhold frequency data just because it has not yet
been processed by dbSNP.) That is the case for rs79866206:<br>
<br>
<a class="moz-txt-link-freetext" href="https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs79866206">https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs79866206</a><br>
<br>
Our live site shows rs1051736170 from dbSNP release 150, with an
allele string of C/A (based on the Human Longevity submission).
These alleles don't match those in the TOPMed and gnomAD VCF's so
the frequency data is not reported. The database we will release
next month uses dbSNP151 and here rs1051736170 has an allele string
of C/G:<br>
<br>
<a class="moz-txt-link-freetext" href="https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs1051736170">https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs1051736170</a><br>
<br>
Our pre-release site is showing the frequency data from gnomAD and
TOPMed as the alleles now match. <br>
<br>
<br>
Best wishes,<br>
<br>
Sarah<br>
<br>
<br>
<div class="moz-cite-prefix">On 27/08/2018 06:24, Fin Swimmer wrote:<br>
</div>
<blockquote type="cite"
cite="mid:a742d8d49c89aadb4ee409639c4426a1@need-login.de">Hello, <br>
<br>
I guess this is more a feature request. It would be fine to have
the possibility to show only variants that have a certain evidence
(gnomAD, ExAC) on the exons page. <br>
<br>
BTW: What's going on by this variants: <br>
<br>
rs79866206 - The evidence "gnomAD" is not set. But there are
population data for it. <br>
rs1051736170 - The evidences "gnomAD" and "TOPMed" are set. But
there are nor population data. <br>
<br>
fin swimmer <br>
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</blockquote>
<br>
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