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--></style></head><body lang=EN-GB link="#0563C1" vlink="#954F72" style='word-wrap:break-word'><div class=WordSection1><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>Dear All,<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>We are pleased to announce that the latest Ensembl and Ensembl Genomes updates have been released:<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><a href="http://www.ensembl.org/" title="http://www.ensembl.org/"><span style='color:black'>http://www.ensembl.org/</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><a href="http://ensemblgenomes.org/" title="http://ensemblgenomes.org/"><span style='color:black'>http://ensemblgenomes.org</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>Highlights of this release include:<o:p></o:p></span></p><ul style='margin-top:0cm' type=disc><li class=MsoNormal style='color:black;mso-list:l0 level1 lfo1'><span style='font-family:"Calibri",sans-serif;color:windowtext'>Update to the Ensembl Canonical transcript set</span><span style='font-family:"Calibri",sans-serif'><o:p></o:p></span></li><li class=MsoNormal style='color:black;mso-list:l0 level1 lfo1;background:white;vertical-align:baseline'><span style='font-family:"Calibri",sans-serif'>Human and mouse genes updated to GENCODE 38 and GENCODE M27, respectively<o:p></o:p></span></li><li class=MsoNormal style='color:black;mso-list:l0 level1 lfo1'><span style='font-family:"Calibri",sans-serif'>Update to the GRCh37 variation and regulation data<o:p></o:p></span></li><li class=MsoNormal style='color:black;mso-list:l0 level1 lfo1;background:white;vertical-align:baseline'><span style='font-family:"Calibri",sans-serif;background:white'>Four new plant species/cultivars</span><span style='font-family:"Calibri",sans-serif'><o:p></o:p></span></li><li class=MsoNormal style='color:black;mso-list:l0 level1 lfo1;background:white;vertical-align:baseline'><span style='font-family:"Calibri",sans-serif;background:white'>New genome assemblies and updated genes for existing species: two birds, one reptile, one fish and two plants</span><span style='font-family:"Calibri",sans-serif'><o:p></o:p></span></li><li class=MsoNormal style='color:black;mso-list:l0 level1 lfo1;background:white;vertical-align:baseline'><span style='font-family:"Calibri",sans-serif;background:white'>New variation data for four vertebrates</span><span style='font-family:"Calibri",sans-serif'><o:p></o:p></span></li><li class=MsoListParagraph style='color:black;mso-list:l0 level1 lfo1'><span style='font-family:"Calibri",sans-serif'>Major data update for 43 metazoans including updated variant consequences and community-based gene annotations from VEuPathDB<o:p></o:p></span></li><li class=MsoListParagraph style='mso-list:l0 level1 lfo1'><span style='font-family:"Calibri",sans-serif'>Retirement of clone-based gene names<o:p></o:p></span></li></ul><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>The release blog post with all news can be viewed here:<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:red'><a href="https://www.ensembl.info/2021/05/05/ensembl-104-has-been-released/">https://www.ensembl.info/2021/05/05/ensembl-104-has-been-released/</a><o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>For the latest news from the Ensembl project visit our blog at:<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><a href="http://www.ensembl.info/"><span style='color:black'>http://www.ensembl.info</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>Best wishes,<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>Michal<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'>On behalf of the Ensembl team<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Calibri",sans-serif;color:black'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>--</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>Michał Szpak, Ph.D.</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>Ensembl Outreach Officer</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>European Bioinformatics Institute (EMBL-EBI)</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>European Molecular Biology Laboratory</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>Wellcome Genome Campus</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;color:black'>Hinxton, Cambridge, CB10 1SD, UK</span><span style='font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;mso-fareast-language:EN-US'><o:p> </o:p></span></p></div></body></html>