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<article itemscope itemtype="http://schema.org/Article" id="post-14231" class="post-14231 post type-post status-publish format-standard hentry category-01-release tag-ensembl tag-ensembl-108 tag-release">
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<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/10/20/ensembl-108-has-been-released/" title="Permalink to Ensembl 108 has been released!" rel="bookmark">Ensembl 108 has been released!</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/10/20/ensembl-108-has-been-released/" rel="bookmark"><time class="entry-date published" datetime="2022-10-20T11:06:01+01:00" itemprop="datepublished">20th October 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/lpmirabueno/" rel="author" itemprop="url"><span itemprop="name">Louisse Mirabueno</span></a></span><span class="sep">·</span><span class="comments-link"><a href="https://www.ensembl.info/2022/10/20/ensembl-108-has-been-released/#respond" itemprop="discussionUrl">0 Comments</a></span></div>
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<p>We are pleased to announce the release of <a href="https://www.ensembl.org/index.html" target="_blank" rel="noreferrer noopener">Ensembl 108</a>, and the corresponding release of <a href="https://ensemblgenomes.org/" target="_blank" rel="noreferrer noopener">Ensembl Genomes 55</a> featuring changes in the human default tracks, new genomes in <a href="https://plants.ensembl.org/index.html">Ensembl Plants</a> and <a href="https://metazoa.ensembl.org/index.html" target="_blank" rel="noreferrer noopener">Ensembl Metazoa</a>, and the addition of mitochondrial annotation for Tasmanian devil.</p>
<p>Genome assemblies and annotation for many new species are also being continuously added to the <a href="https://rapid.ensembl.org/index.html">Ensembl Rapid Release genome browser</a>.</p>
<p>——————————————————————————————–</p>
<h2><strong>Default data display updates for human</strong></h2>
<p>In the Location tab, cDNAs, EST cluster (UniGene) and <a href="https://www.ensembl.org/info/genome/genebuild/ccds.html" target="_blank" rel="noreferrer noopener">CCDS</a> tracks will no longer be displayed by default. These tracks can still be added by configuring the page.</p>
<div class="wp-block-columns">
<div class="wp-block-column">
<figure class="wp-block-image size-large"><img width="692" height="1024" src="https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268OLD-1-692x1024.png" alt="" class="wp-image-14236" srcset="https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268OLD-1-692x1024.png 692w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268OLD-1-203x300.png 203w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268OLD-1-768x1137.png 768w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268OLD-1-1037x1536.png 1037w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268OLD-1.png 1200w" sizes="(max-width: 692px) 100vw, 692px" /><figcaption>A snapshot of the ‘Region in detail’ view in Ensembl release 107.</figcaption></figure>
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<div class="wp-block-column">
<figure class="wp-block-image size-large"><img loading="lazy" width="835" height="1024" src="https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268NEW-1-835x1024.png" alt="" class="wp-image-14237" srcset="https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268NEW-1-835x1024.png 835w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268NEW-1-245x300.png 245w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268NEW-1-768x942.png 768w, https://www.ensembl.info/wp-content/uploads/2022/10/Human_1332315086_32400268NEW-1.png 1200w" sizes="(max-width: 835px) 100vw, 835px" /><figcaption>A snapshot of the ‘Region in detail’ view in Ensembl release 108.</figcaption></figure>
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</div>
<h2><strong>New genomes</strong></h2>
<h3>Plants:</h3>
<p>We have added two new species:</p>
<ul><li><a href="https://plants.ensembl.org/Lolium_perenne/Info/Index"><em>Lolium perenne</em></a> (Rye grass)</li><li><a href="https://plants.ensembl.org/Brassica_juncea/Info/Index"><em>Brassica juncea</em></a> (Brown mustard)</li></ul>
<h3>Metazoa:</h3>
<p>We have expanded the list of metazoa species available on Ensembl, which now includes:</p>
<ul><li><a href="https://metazoa.ensembl.org/Amphibalanus_amphitrite_gca019059575v1"><em>Amphibalanus amphitrite</em></a> (Acorn barnacle)</li><li><a href="https://metazoa.ensembl.org/Acropora_millepora_gca013753865v1"><em>Acropora millepora</em></a> (Stony coral)</li><li><a href="https://metazoa.ensembl.org/Acanthaster_planci_gca001949145v1"><em>Acanthaster planci</em></a><em> </em>(Crown-of-thorns starfish)</li><li><a href="https://metazoa.ensembl.org/Actinia_tenebrosa_gca009602425v1"><em>Actinia tenebrosa</em></a> (Australian red waratah sea anemone)</li><li><a href="https://metazoa.ensembl.org/Asterias_rubens_GCA_902459465.3"><em>Asterias rubens</em></a> (European starfish)</li><li><a href="https://metazoa.ensembl.org/Dimorphilus_gyrociliatus_gca904063045v1"><em>Dimorphilus gyrociliatus</em></a> (Meiobenthic segmented annelid)</li><li><a href="https://metazoa.ensembl.org/Eurytemora_affinis_gca000591075v2"><em>Eurytemora affinis</em></a><em> </em>(Calanoid copepod)</li><li><a href="https://metazoa.ensembl.org/Exaiptasia_diaphana_gca001417965v1"><em>Exaiptasia diaphana</em></a> (Sea anemone)</li><li><a href="https://metazoa.ensembl.org/Homarus_americanus_gca018991925v1"><em>Homarus americanus</em></a> (American lobster)</li><li><a href="https://metazoa.ensembl.org/Hyalella_azteca_gca000764305v2"><em>Hyalella azteca</em></a> (Amphipod)</li><li><a href="https://metazoa.ensembl.org/Hypsibius_exemplaris_gca002082055v1"><em>Hypsibius exemplaris</em></a><em> </em>(Water bear tardigrade)</li><li><a href="https://metazoa.ensembl.org/Mercenaria_mercenaria_gca014805675v2"><em>Mercenaria mercenaria</em></a> (Hard clam)</li><li><a href="https://metazoa.ensembl.org/Mizuhopecten_yessoensis_gca002113885v2"><em>Mizuhopecten yessoensis</em></a><em> </em>(Yesso scallop)</li><li><a href="https://metazoa.ensembl.org/Octopus_sinensis_gca006345805v1"><em>Octopus sinensis</em></a><em> </em>(East Asian common octopus)</li><li><a href="https://metazoa.ensembl.org/Owenia_fusiformis_gca903813345v1"><em>Owenia fusiformis</em></a><em> </em>(Polychaete annelid)</li><li><a href="https://metazoa.ensembl.org/Patiria_miniata_gca015706575v1"><em>Patiria miniata</em></a><em> </em>(Bat star starfish)</li><li><a href="https://metazoa.ensembl.org/Penaeus_japonicus_gca017312705v1"><em>Penaeus japonicus</em></a><em> </em>(Kuruma shrimp)</li><li><a href="https://metazoa.ensembl.org/Penaeus_vannamei_gca003789085v1"><em>Penaeus vannamei</em></a> (Pacific white shrimp)</li><li><a href="https://metazoa.ensembl.org/Pollicipes_pollicipes_gca011947565v2"><em>Pollicipes pollicipes</em></a><em> </em>(Gooseneck barnacle)</li><li><a href="https://metazoa.ensembl.org/Portunus_trituberculatus_gca017591435v1"><em>Portunus trituberculatus</em></a> (Swimming crab)</li><li><a href="https://metazoa.ensembl.org/Procambarus_clarkii_gca020424385v2"><em>Procambarus clarkii</em></a> (Red swamp crayfish)</li></ul>
<h2><strong>New Assemblies and/or Annotation</strong></h2>
<h3>Vertebrates:</h3>
<ul><li>Mitochondrial annotation for <a href="https://www.ensembl.org/Sarcophilus_harrisii/Info/Index"><em>Sarcophilus harrisii</em> (Tasmanian devil, mSarHar1.11)</a> have been added. </li><li>RNASeq tracks including data from the <a href="https://www.gene-switch.eu/" target="_blank" rel="noreferrer noopener">GeneSWitCH consortium</a> for <em>Gallus gallus</em> (chicken) <a href="https://www.ensembl.org/Gallus_gallus">reference (GRCg7b)</a> and <a href="https://www.ensembl.org/Gallus_gallus_GCA_016700215.2">chicken breed (GRCg7w)</a> have been added.</li><li>Variation data from the <a rel="noreferrer noopener" href="https://www.ebi.ac.uk/eva/" target="_blank">European Variation Archive (EVA)</a> are now displayed for five additional species: <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Macaca_fascicularis" target="_blank">Macaca fascicularis</a></em> (crab-eating macaque),<em> <a rel="noreferrer noopener" href="https://www.ensembl.org/Sander_lucioperca" target="_blank">Sander lucioperca</a> </em>(pike-perch), <a rel="noreferrer noopener" href="https://www.ensembl.org/Microtus_ochrogaster" target="_blank"><em>Microtus ochrogaster</em></a> (prairie vole), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Coturnix_japonica" target="_blank">Coturnix japonica</a> </em>(Japanese quail) and <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Ficedula_albicollis" target="_blank">Ficedula albicollis</a></em> (collared flycatcher). </li></ul>
<h3>Metazoa:</h3>
<p>We have updated the assembly and genome annotation of:</p>
<ul><li><em><a href="https://metazoa.ensembl.org/Daphnia_magna_gca020631705v2/Info/Index" target="_blank" rel="noreferrer noopener">Daphnia magna</a></em> (Fresh water planktonic crustacean)</li><li><em><a href="https://metazoa.ensembl.org/Lingula_anatina_gca001039355v2" target="_blank" rel="noreferrer noopener">Lingula anatina</a></em> (Lamp shell)</li></ul>
<p>We have also updated the genome annotation of:</p>
<ul><li><a href="https://metazoa.ensembl.org/Caenorhabditis_elegans/Info/Index?db=core"><em>Caenorhabditis elegans</em></a> to <a href="https://wormbase.org//#012-34-5">WormBase</a> annotation WS282.</li><li>RefSeq variation annotation has been added to <em><a href="https://metazoa.ensembl.org/Octopus_bimaculoides_gca001194135v1/Info/Index" target="_blank" rel="noreferrer noopener">Octopus bimaculoides</a></em> (California two-spot octopus)</li></ul>
<h2><strong>Other updates and changes</strong></h2>
<ul><li>Our variant databases for<em> <a rel="noreferrer noopener" href="https://www.ensembl.org/Bos_taurus/Info/Index" target="_blank">Bos taurus</a></em> (cow), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Danio_rerio" target="_blank">Danio rerio</a> </em>(zebrafish), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Equus_caballus" target="_blank">Equus caballus</a></em> (horse), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Felis_catus" target="_blank">Felis catus</a></em> (cat), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Gallus_gallus_GCA_000002315.5" target="_blank">Gallus gallus</a></em> (Red Jungle fowl chicken), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Macaca_mulatta" target="_blank">Macaca mulatta</a> </em>(macaque), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Mus_musculus/Info/Index" target="_blank">Mus musculus</a></em> (mouse), <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Rattus_norvegicus" target="_blank">Rattus norvegicus</a></em> (rat) and <em><a rel="noreferrer noopener" href="https://www.ensembl.org/Sus_scrofa" target="_blank">Sus scrofa</a></em> (pig) have been updated to use <a rel="noreferrer noopener" href="https://www.ebi.ac.uk/about/news/updates-from-data-resources/european-variation-archive-release-3-over-540-million-unique-variants/" target="_blank">EVA release 3</a>. This replaces previous data from dbSNP and uses new clustering and quality control methods, for example, variants which do not match the genome assembly will no longer be shown.</li><li><a rel="noreferrer noopener" href="https://www.ensembl.org/info/genome/genebuild/mane.html" target="_blank">MANE transcripts</a> and proteins are now highlighted on gene and transcript summary pages. This gives more prominence to MANE and reduces the significance on <a rel="noreferrer noopener" href="https://www.ensembl.org/info/genome/genebuild/ccds.html" target="_blank">CCDS</a>.</li><li>The <em>transcribed_unprocessed_pseudogene</em> biotype was changed to have separate pseudogene and lncRNA gene IDs in human and mouse, which increased the number of lncRNA genes in the total gene count. </li><li>The biotype <em>processed_transcript</em>, when present in protein coding loci, has been replaced with <em>protein_coding_CDS_not_defined</em>. </li><li>The Post-GWAS tool has been retired (read more here: <a href="https://www.ensembl.info/2022/07/28/retiring-the-post-gwas-tool/">https://www.ensembl.info/2022/07/28/retiring-the-post-gwas-tool/</a>). </li><li>Peak features have been removed from overlap <a rel="noreferrer noopener" href="https://rest.ensembl.org/" target="_blank">REST endpoints</a>, which may affect queries. </li><li><em>Aphanomyces astaci</em>, <em>Aphanomyces invadans</em>, <em>Globisporangium ultimum</em>, and <em>Hyaloperonospora arabidopsidis</em> have been removed from <a rel="noreferrer noopener" href="https://fungi.ensembl.org/index.html" target="_blank">Ensembl Fungi</a>, and fungal gene trees have been re-computed. These species will continue to be included in <a rel="noreferrer noopener" href="https://protists.ensembl.org/index.html" target="_blank">Ensembl Protists</a>.</li><li>Retirement of Ensembl 90 archive.</li></ul>
<p></p>
</div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14205" class="post-14205 post type-post status-publish format-standard hentry category-02-ensembl-vep tag-alphafold tag-protein tag-protein-structure tag-variant-effect-predictor tag-vep">
<header class="entry-header">
<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/08/26/cool-stuff-ensembl-vep-can-do-display-variants-on-alphafold-predicted-3d-protein-structures/" title="Permalink to Cool stuff Ensembl VEP can do: display variants on AlphaFold-predicted 3D protein structures" rel="bookmark">Cool stuff Ensembl VEP can do: display variants on AlphaFold-predicted 3D protein structures</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/08/26/cool-stuff-ensembl-vep-can-do-display-variants-on-alphafold-predicted-3d-protein-structures/" rel="bookmark"><time class="entry-date published" datetime="2022-08-26T09:37:59+01:00" itemprop="datepublished">26th August 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/bmoore/" rel="author" itemprop="url"><span itemprop="name">Ben (Outreach)</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on Cool stuff Ensembl VEP can do: display variants on AlphaFold-predicted 3D protein structures</span></span></span></div>
</header>
<div class="entry-content" itemprop="articleBody">
<p>The AlphaFold AI system developed by <a rel="noreferrer noopener" href="https://deepmind.com/" target="_blank">DeepMind</a> predicts a protein’s 3D structure from its amino acid sequence. You can now view variant locations on AlphaFold predicted structures in the Ensembl VEP web tool.</p>
<a class="btn btn-default btn-sm" href="https://www.ensembl.info/2022/08/26/cool-stuff-ensembl-vep-can-do-display-variants-on-alphafold-predicted-3d-protein-structures/">Continue reading <i class="fa fa-angle-double-right"></i></a> </div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14140" class="post-14140 post type-post status-publish format-standard hentry category-05-community tag-bioinformatics tag-career tag-ensembl tag-genomics tag-outreach tag-scicomm">
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<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/08/22/getting-to-know-us-aleena-from-outreach/" title="Permalink to Getting to know us: Aleena from Outreach" rel="bookmark">Getting to know us: Aleena from Outreach</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/08/22/getting-to-know-us-aleena-from-outreach/" rel="bookmark"><time class="entry-date published" datetime="2022-08-22T14:00:00+01:00" itemprop="datepublished">22nd August 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/lpmirabueno/" rel="author" itemprop="url"><span itemprop="name">Louisse Mirabueno</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on Getting to know us: Aleena from Outreach</span></span></span></div>
</header>
<div class="entry-content" itemprop="articleBody">
<p>In this post, we are getting to know <a rel="noreferrer noopener" href="https://www.ebi.ac.uk/people/person/aleena-mushtaq" target="_blank">Aleena Mushtaq</a> from the Outreach team, who are (interestingly) also in charge of the Ensembl blog! Aleena tells us of the diverse workload of an outreach officer, the public engagement programmes she is involved in, and what she does in her free-time. </p>
<a class="btn btn-default btn-sm" href="https://www.ensembl.info/2022/08/22/getting-to-know-us-aleena-from-outreach/">Continue reading <i class="fa fa-angle-double-right"></i></a> </div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14178" class="post-14178 post type-post status-publish format-standard hentry category-01-release tag-ensembl-108 tag-ensembl-genomes-55 tag-release tag-release-108">
<header class="entry-header">
<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/08/18/whats-coming-in-ensembl-release-108-ensembl-genomes-55/" title="Permalink to What’s coming in Ensembl release 108 / Ensembl Genomes 55?" rel="bookmark">What’s coming in Ensembl release 108 / Ensembl Genomes 55?</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/08/18/whats-coming-in-ensembl-release-108-ensembl-genomes-55/" rel="bookmark"><time class="entry-date published" datetime="2022-08-18T12:52:15+01:00" itemprop="datepublished">18th August 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/lpmirabueno/" rel="author" itemprop="url"><span itemprop="name">Louisse Mirabueno</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on What’s coming in Ensembl release 108 / Ensembl Genomes 55?</span></span></span></div>
</header>
<div class="entry-content" itemprop="articleBody">
<p>Ensembl 108 and Ensembl Genomes 55 are expected to be released in September 2022. Check out what we are up to, although we cannot guarantee everything listed here will make it into the final release.</p>
<a class="btn btn-default btn-sm" href="https://www.ensembl.info/2022/08/18/whats-coming-in-ensembl-release-108-ensembl-genomes-55/">Continue reading <i class="fa fa-angle-double-right"></i></a> </div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14136" class="post-14136 post type-post status-publish format-standard hentry category-07-status tag-mirrors tag-service-status">
<header class="entry-header">
<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/08/05/downtime-of-ensembl-mirror-sites/" title="Permalink to Downtime of Ensembl mirror sites" rel="bookmark">Downtime of Ensembl mirror sites</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/08/05/downtime-of-ensembl-mirror-sites/" rel="bookmark"><time class="entry-date published" datetime="2022-08-05T13:48:29+01:00" itemprop="datepublished">5th August 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/bmoore/" rel="author" itemprop="url"><span itemprop="name">Ben (Outreach)</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on Downtime of Ensembl mirror sites</span></span></span></div>
</header>
<div class="entry-content" itemprop="articleBody">
<p>As part of ongoing work to improve the performance and reliability of our <a href="https://www.ensembl.org/info/about/mirrors.html" target="_blank" rel="noreferrer noopener">mirror sites</a>, we will be upgrading the underlying website architecture. While the upgrade takes place, the Ensembl mirror sites (<a href="https://uswest.ensembl.org/index.html?redirect=no">USWest</a>, <a href="http://useast.ensembl.org/index.html?redirect=no" target="_blank" rel="noreferrer noopener">USEast </a>and <a href="http://asia.ensembl.org/index.html?redirect=no" target="_blank" rel="noreferrer noopener">Asia</a>) will be intermittently unavailable for short periods between Monday 8th August and Friday 12th August 2022.</p>
<a class="btn btn-default btn-sm" href="https://www.ensembl.info/2022/08/05/downtime-of-ensembl-mirror-sites/">Continue reading <i class="fa fa-angle-double-right"></i></a> </div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14129" class="post-14129 post type-post status-publish format-standard hentry category-02-ensembl-vep tag-intact tag-variant-effect-predictor tag-vep">
<header class="entry-header">
<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/07/29/cool-stuff-ensembl-vep-can-do-provide-evidence-of-protein-interaction-impact/" title="Permalink to Cool stuff Ensembl VEP can do – provide evidence of protein interaction impact" rel="bookmark">Cool stuff Ensembl VEP can do – provide evidence of protein interaction impact</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/07/29/cool-stuff-ensembl-vep-can-do-provide-evidence-of-protein-interaction-impact/" rel="bookmark"><time class="entry-date published" datetime="2022-07-29T10:00:34+01:00" itemprop="datepublished">29th July 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/bmoore/" rel="author" itemprop="url"><span itemprop="name">Ben (Outreach)</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on Cool stuff Ensembl VEP can do – provide evidence of protein interaction impact</span></span></span></div>
</header>
<div class="entry-content" itemprop="articleBody">
<p><a rel="noreferrer noopener" href="https://www.ensembl.org/info/docs/tools/vep/index.html" target="_blank">Ensembl VEP</a> integrates information from many different resources to help you interpret the functional impact of your variants. It now reports when variants fall in sites with evidence of impact on protein interactions, as described in the IntAct database.</p>
<a class="btn btn-default btn-sm" href="https://www.ensembl.info/2022/07/29/cool-stuff-ensembl-vep-can-do-provide-evidence-of-protein-interaction-impact/">Continue reading <i class="fa fa-angle-double-right"></i></a> </div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14124" class="post-14124 post type-post status-publish format-standard hentry category-03-other tag-postgap tag-retirement">
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<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/07/28/retiring-the-post-gwas-tool/" title="Permalink to Retiring the Post-GWAS tool" rel="bookmark">Retiring the Post-GWAS tool</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/07/28/retiring-the-post-gwas-tool/" rel="bookmark"><time class="entry-date published" datetime="2022-07-28T11:43:22+01:00" itemprop="datepublished">28th July 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/bmoore/" rel="author" itemprop="url"><span itemprop="name">Ben (Outreach)</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on Retiring the Post-GWAS tool</span></span></span></div>
</header>
<div class="entry-content" itemprop="articleBody">
<p>The Post-GWAS tool will be retired in Ensembl 108.</p>
<a class="btn btn-default btn-sm" href="https://www.ensembl.info/2022/07/28/retiring-the-post-gwas-tool/">Continue reading <i class="fa fa-angle-double-right"></i></a> </div>
</article>
<article itemscope itemtype="http://schema.org/Article" id="post-14114" class="post-14114 post type-post status-publish format-standard hentry category-07-status tag-service-status">
<header class="entry-header">
<h2 class="entry-title" itemprop="name">
<a itemprop="url" href="https://www.ensembl.info/2022/07/20/disruption-to-ensembl-services-4/" title="Permalink to Disruption to Ensembl services" rel="bookmark">Disruption to Ensembl services</a>
</h2>
<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/07/20/disruption-to-ensembl-services-4/" rel="bookmark"><time class="entry-date published" datetime="2022-07-20T14:29:11+01:00" itemprop="datepublished">20th July 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/bmoore/" rel="author" itemprop="url"><span itemprop="name">Ben (Outreach)</span></a></span><span class="sep">·</span><span class="comments-link"><a href="https://www.ensembl.info/2022/07/20/disruption-to-ensembl-services-4/#comments" itemprop="discussionUrl">2 Comments</a></span></div>
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<p>Due to scheduled maintenance work, a number of Ensembl services will be temporarily unavailable between Tuesday 26th July 2022, 15:00 (BST) and Wednesday 27th July 2022, 13:00 (BST).</p>
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<article itemscope itemtype="http://schema.org/Article" id="post-14097" class="post-14097 post type-post status-publish format-standard hentry category-01-release tag-ensembl tag-ensembl-genomes tag-genomics tag-gnomad tag-metazoa tag-plants tag-release tag-vep">
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<a itemprop="url" href="https://www.ensembl.info/2022/07/12/ensembl-107-has-been-released/" title="Permalink to Ensembl 107 has been released!" rel="bookmark">Ensembl 107 has been released!</a>
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<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/07/12/ensembl-107-has-been-released/" rel="bookmark"><time class="entry-date published" datetime="2022-07-12T13:32:02+01:00" itemprop="datepublished">12th July 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/aleena/" rel="author" itemprop="url"><span itemprop="name">Aleena Mushtaq</span></a></span><span class="sep">·</span><span class="comments-link"><a href="https://www.ensembl.info/2022/07/12/ensembl-107-has-been-released/#comments" itemprop="discussionUrl">2 Comments</a></span></div>
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<div class="entry-content" itemprop="articleBody">
<p>Ensembl 107 and Ensembl Genomes 54 have now been released. Check out our site for exciting new updates to regulatory annotations, updated vertebrate genomes and lots of new metazoan species.</p>
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<article itemscope itemtype="http://schema.org/Article" id="post-14082" class="post-14082 post type-post status-publish format-standard hentry category-05-community tag-annotation tag-bioinformatician tag-bioinformatics tag-career tag-ensembl tag-genebuild tag-genomics tag-outreach tag-scicomm">
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<a itemprop="url" href="https://www.ensembl.info/2022/07/06/getting-to-know-us-jose-from-genebuild/" title="Permalink to Getting to know us: José from Genebuild" rel="bookmark">Getting to know us: José from Genebuild</a>
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<div class="entry-meta"><span class="entry-date"><a href="https://www.ensembl.info/2022/07/06/getting-to-know-us-jose-from-genebuild/" rel="bookmark"><time class="entry-date published" datetime="2022-07-06T14:49:14+01:00" itemprop="datepublished">6th July 2022</time></a></span> by <span class="author vcard" itemscope itemprop="author" itemtype="http://schema.org/Person"><a class="url fn n" href="https://www.ensembl.info/author/lpmirabueno/" rel="author" itemprop="url"><span itemprop="name">Louisse Mirabueno</span></a></span><span class="sep">·</span><span class="comments-link"><span>Comments Off<span class="screen-reader-text"> on Getting to know us: José from Genebuild</span></span></span></div>
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<p>Meet <a href="https://www.ebi.ac.uk/about/people/jose-maria-gonzalez-perez-silva">José María González Pérez-Silva</a> from the Genebuild team! José describes his work at Ensembl, the experience he had during his university studies, and how he winds down when not surrounded by annotation data. </p>
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