<div dir="ltr"><div dir="ltr">Hi Thomas,<div><br></div><div>Thank you for your response.</div><div>I am interested in loading the GERP and associated alignment data into Python,  not necessarily from an EMF file. </div><div>Right now I loaded the human genome and gerp scores separately from release 109 FTP, matching them by position. </div><div>I would similarly like to be able to get the gerp for an entire alignment. </div><div><br></div><div>Best</div><div>Omar</div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Wed, Mar 8, 2023 at 5:56 PM Thomas Walsh <<a href="mailto:twalsh@ebi.ac.uk">twalsh@ebi.ac.uk</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div style="font-size:10pt;font-family:Verdana,Geneva,sans-serif">
<p>Hello Omar,</p>
<p>My name is Thomas Walsh from the Ensembl Compara team, and I helped create the EMF files that you've expressed an interest in.</p>
<p>I understand that you're especially interested in accessing GERP and alignment data together. Is it necessary for this to be taken from an EMF file? Or are you primarily interested in loading the GERP and associated alignment data into Python, regardless of how it got there?</p>
<p>All the best,</p>
<p>Thomas Walsh.</p>
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<p>-------- Forwarded Message --------<br>Subject: [ensembl-dev] Python Script to read emf dump files?<br>Date: Thu, 2 Mar 2023 13:21:18 -0500<br>From: Omar Gamel <<a href="mailto:omar.gamel@utoronto.ca" target="_blank">omar.gamel@utoronto.ca</a>><br>Reply-To: Ensembl developers list <<a href="mailto:dev@ensembl.org" target="_blank">dev@ensembl.org</a>><br>To: <a href="mailto:dev@ensembl.org" target="_blank">dev@ensembl.org</a></p>
<p>Hello,</p>
<p>I am looking for a python package or script that can parse the alignment emf files in the ENSEMBL FTP dump into an object I can manipulate<br>Example files here: <a href="https://ftp.ensembl.org/pub/current_emf/ensembl-compara/multiple_alignments/90_mammals.epo_extended/" target="_blank">https://ftp.ensembl.org/pub/current_emf/ensembl-compara/multiple_alignments/90_mammals.epo_extended/</a><br>I am particularly interested in the GERP data along with the alignment.</p>
<p>I see the example scripts provided are largely in perl: <a href="https://github.com/Ensembl/ensembl-compara/tree/release/109/scripts/dumps" target="_blank">https://github.com/Ensembl/ensembl-compara/tree/release/109/scripts/dumps</a></p>
<p>Please let me know where I can find such a python resource.</p>
<p>Thank you<br>Omar</p>
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<p><strong><span>Thomas Walsh</span></strong></p>
<p><strong>Bioinformatics Developer, Ensembl Compara</strong></p>
<p><span>European Bioinformatics Institute (EMBL-EBI)</span></p>
<p><span>Wellcome Genome Campus</span></p>
<p><span>Hinxton</span></p>
<p><span>Cambridge CB10 1SD</span></p>
<p><span>United Kingdom</span></p>
<p><span>Email: <a href="mailto:twalsh@ebi.ac.uk" target="_blank">twalsh@ebi.ac.uk</a></span></p>
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