<html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"></head><body style="overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;">Hi Tarik, <div><br></div><div>Thank you for the query. Yes - the changes will be available through the REST API for 115. </div><div><br></div><div>While Clinvar updates <a href="https://www.ncbi.nlm.nih.gov/clinvar/docs/faq/">monthly</a>, schema changes are very infrequent. </div><div><br></div><div>The monthly Clinvar update file is frozen during Ensembl’s production process, and the version used in the Ensembl release is listed here:</div><div><br></div><div><a href="https://www.ensembl.org/info/genome/variation/species/sources_documentation.html">https://www.ensembl.org/info/genome/variation/species/sources_documentation.html</a> </div><div><br></div><div>Cheers</div><div>Jorge</div><div><br></div><div><br></div><div><div>
Dr Jorge Batista da Rocha<br>Ensembl Outreach Project Leader<br>European Bioinformatics Institute (EMBL-EBI)
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<div><br><blockquote type="cite"><div>On 22 Aug 2025, at 08:29, Tarik Luisman <tarik@genescape.nl> wrote:</div><br class="Apple-interchange-newline"><div><div dir="ltr"><div><div>Good morning,</div><div dir="auto"><br></div><div dir="auto">I see a clinvar update is coming in Ensembl release 115, which is great. (Does this also count for the REST API?)</div><div dir="auto"><br></div><div dir="auto">And what is the usual update frequency for clinvar data?</div><div dir="auto"><br></div><div dir="auto">Kind regards,</div><div><br></div></div><div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><font face="arial black, sans-serif" style="font-family: "arial black", sans-serif;">Tarik Luisman</font><div style="color:rgb(34,34,34)">Chief Technology Officer</div><div style="color:rgb(34,34,34)"><a href="http://www.genescape.nl/" style="color:rgb(17,85,204)" target="_blank">GeneScape</a></div></div></div></div></div>
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