<div class="gmail_quote">Kiran, Daniel-</div><div class="gmail_quote">Thanks for the suggestion and warnings regarding loading RefSeqs directly. I'm going to start up a new thread asking this explicitly. </div><div class="gmail_quote">
<br></div><div class="gmail_quote">Paul-</div><div>I completely agree that it is better to use a reference assembly sequence rather than the sequence in the RefSeq. I intend to use RefSeqs solely for the exon structure which is the only way to map HGVS variants that are based on NCBI sequences to the reference genome in the general case. Or, am I missing something?</div>
<div><br></div><div>-Reece</div><div><br></div>